Quartz crystal microbalance sorption sensors essentially weigh
the amount of gas or vapour interacting with a sensing layer coated onto a microbalance.
The process is essentially a single step sensing mechanism
followed by a separate transduction step - direct weighing of the interacting analyte. In
conductimetric sensors the interaction and transduction step (conduction change) are
coupled. This feature has the advantage of allowing the array designer to optimise a
single, well understood interaction - the gas/coating interaction. A wide range of well
understood and stable coatings such as gas chromatography (GC) stationary phases can be
utilised .
Cross-section of a microbalance sensor showing the gas partition process.
The weighing step makes certain assumptions in the performance of
the coating in the presence of different vapours and the array designer will need to
validate the coating experimentally. However, once suitable coatings have been selected,
the inherent reliability of the quartz microbalance and coatings mean that stable and
highly repeatable array fabrication is possible.